Utilization of Intestinal Probiotics to Improve the Degradation and Absorption of Food and Drug Homologous Flavonoids

Under the condition that the slow degradation rate of flavone in food in the gastrointestinal tract of the human body has long been a problem for researchers, we constructed and justified a protein to improve the degradation and absorption rate of flavone. The paper, through methods including polymerase chain reaction and gel electrophoresis, explores the possible solution for increasing degradation rate with a flr gene. The FLR enzyme produced throughout the experiment would successfully degrade flavonoids into deamination tyrosine (DAT) to achieve the goal of having anti-inflammatory function. The paper concludes that with E. Coli carrying Pet28a-flr-chi-enoR-phy, flavonoids tested can be dissolved and decomposed up to 95% within 6 hours.