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APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis
Completed
Group Leader:
N/A
Yuanlin Wang 1,†, Yan Fan 2,†, Yi Jiang 1, Enquan Wang 1, Yu Song 1, Hongguang Chen 1, Feier Xu 1, Keliang Xie 2,* and Yonghao Yu 1,*
Group Members:
Target biomarkers for H2 at both the protein and genome levels are still unclear. In this study, quantitative proteomics acquired from a mouse model were first analyzed. At the same time, functional pathway analysis helped identify functional pathways at the protein level. Then, bioinformatics on mRNA sequencing data were conducted between sepsis and normal mouse models.
Published in the International Journal of Molecular Sciences (https://www.mdpi.com/1422-0067/24/14/11325)
Author Notes:
1 Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin 300052, China; wyl1996@tmu.edu.cn (Y.W.); jiangyi@tmu.edu.cn (Y.J.); enquanwang20162021@gmail.com (E.W.);
15822686071@163.com (Y.S.); hongguangchen@tmu.edu.cn(H.C.); sophiaxufeier@gmail.com (F.X.)
2 Department of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China; fanyan1120@tmu.edu.cn
* Correspondence: kxie@tmu.edu.cn (K..); yyu@tmu.edu.cn (Y.Y.)
† These authors contributed equally to this work.
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